Hypoxic colorectal cancer‐derived extracellular vesicles deliver microRNA‐361‐3p to facilitate cell proliferation by targeting TRAF3 via the noncanonical NF‐κB pathways

Hypoxic colorectal cancer‐derived extracellular vesicles deliver microRNA‐361‐3p to facilitate cell proliferation by targeting TRAF3 via the noncanonical NF‐κB pathways

Abstract Background Hypoxic tumour microenvironment (TME) is a key regulator in cancer progression. However, the communications between hypoxic cells and other components in TME during colorectal cancer (CRC) progression via extracellular vesicles (EVs) remain unclear. Methods High‐throughput sequen...

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Bibliographic Details
Main Authors: Jie Li, Peng Yang, Fangyu Chen, Yuqian Tan, Changzhi Huang, Hengyang Shen, Chaofan Peng, Yifei Feng, Yueming Sun
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Clinical and Translational Medicine
Subjects:
colorectal cancer
extracellular vesicles
hypoxia
miR‐361‐3p
noncanonical NF‐κB
Online Access:https://doi.org/10.1002/ctm2.349

Internet

https://doi.org/10.1002/ctm2.349

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