Molecular mechanism of cyclodextrin mediated cholesterol extraction.
The depletion of cholesterol from membranes, mediated by β-cyclodextrin (β-CD) is well known and documented, but the molecular details of this process are largely unknown. Using molecular dynamics simulations, we have been able to study the CD mediated extraction of cholesterol from model membranes,...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-03-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3063748?pdf=render |