Effective control of chronic gamma-herpesvirus infection by unconventional MHC Class Ia-independent CD8 T cells.

Control of virus infection is mediated in part by major histocompatibility complex (MHC) Class Ia presentation of viral peptides to conventional CD8 T cells. Although important, the absolute requirement for MHC Class Ia-dependent CD8 T cells for control of chronic virus infection has not been formal...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-05-01
Series:PLoS Pathogens
Online Access:http://dx.doi.org/10.1371/journal.ppat.0020037