Modulation of complement activation by pentraxin-3 in prostate cancer

Abstract Pentraxin 3 (PTX3) is an essential component of the innate immune system and a recognized modulator of Complement cascade. The role of Complement system in the pathogenesis of prostate cancer has been largely underestimated. The aim of our study was to investigate the role of PTX3 as possib...

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Bibliographic Details
Main Authors: Giovanni Stallone, Giuseppe Stefano Netti, Luigi Cormio, Giuseppe Castellano, Barbara Infante, Paola Pontrelli, Chiara Divella, Oscar Selvaggio, Federica Spadaccino, Elena Ranieri, Francesca Sanguedolce, Antonio Pennella, Loreto Gesualdo, Giuseppe Carrieri, Giuseppe Grandaliano
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-75376-z