Primary decidual zone formation requires Scribble for pregnancy success in mice

The scaffold protein Scribble (Scrib) has roles in PCP and tight junction formation. Here the authors show that during embryo implantation in mouse, Scrib is needed to form the avascular primary decidual zone by transforming stromal cells into an epithelial cell-like barrier around the crypt, protec...

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Bibliographic Details
Main Authors: Jia Yuan, Shizu Aikawa, Wenbo Deng, Amanda Bartos, Gerd Walz, Florian Grahammer, Tobias B. Huber, Xiaofei Sun, Sudhansu K. Dey
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13489-4