Comparative Proteomic Analysis of Histoplasma capsulatum Yeast and Mycelium Reveals Differential Metabolic Shifts and Cell Wall Remodeling Processes in the Different Morphotypes

Histoplasma capsulatum is a thermally dimorphic fungus distributed worldwide, but with the highest incidence in the Americas within specific geographic areas, such as the Mississippi River Valley and regions in Latin America. This fungus is the etiologic agent of histoplasmosis, an important life-th...

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Main Authors: Marcos Abreu Almeida, Lilian Cristiane Baeza, Rodrigo Almeida-Paes, Alexandre Melo Bailão, Clayton Luiz Borges, Allan Jefferson Guimarães, Célia Maria Almeida Soares, Rosely Maria Zancopé-Oliveira
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.640931/full