Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A.

Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A.

Chromosome duplication and transmission into daughter cells requires the precisely orchestrated binding and release of cohesin. We found that the Drosophila histone chaperone NAP1 is required for cohesin release and sister chromatid resolution during mitosis. Genome-wide surveys revealed that NAP1 a...

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Bibliographic Details
Main Authors: Yuri M Moshkin, Cecile M Doyen, Tsung-Wai Kan, Gillian E Chalkley, Karen Sap, Karel Bezstarosti, Jeroen A Demmers, Zeliha Ozgur, Wilfred F J van Ijcken, C Peter Verrijzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3784504?pdf=render

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http://europepmc.org/articles/PMC3784504?pdf=render

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