Mitochondrial Dysfunction in Chemotherapy-Induced Peripheral Neuropathy (CIPN)
The mitochondrial dysfunction has a critical role in several disorders including chemotherapy-induced peripheral neuropathies (CIPN). This is due to a related dysregulation of pathways involving calcium signalling, reactive oxygen species and apoptosis. Vincristine is able to affect calcium movement...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2015-06-01
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| Series: | Toxics |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2305-6304/3/2/198 |