Blood-brain barrier genetic disruption leads to protective barrier formation at the Glia Limitans.
Inflammation of the central nervous system (CNS) induces endothelial blood-brain barrier (BBB) opening as well as the formation of a tight junction barrier between reactive astrocytes at the Glia Limitans. We hypothesized that the CNS parenchyma may acquire protection from the reactive astrocytic Gl...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-11-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000946 |