Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson’s disease
Abstract Iron accumulates gradually in the ageing brain. In Parkinson’s disease, iron deposition within the substantia nigra is further increased, contributing to a heightened pro-oxidant environment in dopaminergic neurons. We hypothesise that individuals in high-income countries, where cereals and...
Main Authors: | Dominic J Hare, Bárbara Rita Cardoso, Erika P Raven, Kay L Double, David I Finkelstein, Ewa A Szymlek-Gay, Beverley-Ann Biggs |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-01-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-016-0004-y |
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