LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling

LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling

Long noncoding RNAs (lncRNAs) play important roles in regulating diverse cellular processes in the vessel wall, including atherosclerosis. RNA-Seq profiling of intimal lesions revealed a lncRNA, VINAS (Vascular INflammation and Atherosclerosis lncRNA Sequence), that is enriched in the aortic intima...

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Bibliographic Details
Main Authors: Viorel Simion, Haoyang Zhou, Jacob B. Pierce, Dafeng Yang, Stefan Haemmig, Yevgenia Tesmenitsky, Galina Sukhova, Peter H. Stone, Peter Libby, Mark W. Feinberg
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-11-01
Series:JCI Insight
Subjects:
Vascular biology
Online Access:https://doi.org/10.1172/jci.insight.140627

Internet

https://doi.org/10.1172/jci.insight.140627

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