Production of Putative Diterpene Carboxylic Acid Intermediates of Triptolide in Yeast

Production of Putative Diterpene Carboxylic Acid Intermediates of Triptolide in Yeast

The development of medical applications exploiting the broad bioactivities of the diterpene therapeutic triptolide from Tripterygium wilfordii is limited by low extraction yields from the native plant. Furthermore, the extraordinarily high structural complexity prevents an economically attractive en...

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Bibliographic Details
Main Authors: Victor Forman, Roberta Callari, Christophe Folly, Harald Heider, Björn Hamberger
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Molecules
Subjects:
triptolide
dehydroabietic acid
miltiradienic acid
miltiradiene
dehydroabietadiene
medicinal diterpenes
Saccharomyces cerevisiae
Nicotiana benthamiana
Tripterygium wilfordii
Online Access:http://www.mdpi.com/1420-3049/22/6/981

Internet

http://www.mdpi.com/1420-3049/22/6/981

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