Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein

<p>Abstract</p> <p>Background</p> <p>The human immunodeficiency virus type 1 (HIV-1) Tat protein is a major viral transactivator required for HIV-1 replication. In the nucleus Tat greatly stimulates the synthesis of full-length transcripts from the HIV-1 promoter by cau...

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Bibliographic Details
Main Authors: López-Lastra Marcelo, Ohlmann Théophile, Soto-Rifo Ricardo, Ivanyi-Nagy Roland, Charnay Nicolas, Darlix Jean-Luc
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/74