Value of the Overall Pneumococcal Polysaccharide Response in the Diagnosis of Primary Humoral Immunodeficiencies

Value of the Overall Pneumococcal Polysaccharide Response in the Diagnosis of Primary Humoral Immunodeficiencies

BackgroundAn overall response assay [OVA, based on a 23-valent pneumococcal polysaccharide vaccine (PPV23)] is widely used to screen for anti-pneumococcal antibodies. Given the heterogeneity of response from one polysaccharide (PS) to another, a World Health Organization-standardized serotype-specif...

Full description

Bibliographic Details
Main Authors: Benjamin Lopez, Mathilde Bahuaud, Claire Fieschi, Souad Mehlal, Mohamed Jeljeli, Stéphanie Rogeau, Séverine Brabant, Anne-Sophie Deleplancque, Sylvain Dubucquoi, Sandrine Poizot, Louis Terriou, David Launay, Frédéric Batteux, Myriam Labalette, Guillaume Lefèvre
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
primary immunodeficiency
humoral immunodeficiency
pneumococcal polysaccharide response
serotype-specific assay
polysaccharide response
overall assay
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01862/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01862/full

Similar Items