Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis

Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis

The outer-membrane of Gram-negative bacteria is critical for surface adhesion, pathogenicity, antibiotic resistance and survival. The major constituent – hydrophobic β-barrel Outer-Membrane Proteins (OMPs) – are first secreted across the inner-membrane through the Sec-translocon for delivery to peri...

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Bibliographic Details
Main Authors: Sara Alvira, Daniel W Watkins, Lucy Troman, William J Allen, James S Lorriman, Gianluca Degliesposti, Eli J Cohen, Morgan Beeby, Bertram Daum, Vicki AM Gold, J Mark Skehel, Ian Collinson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
BAM complex
sec complex
holotranslocon
outer membrane protein
HTL-BAM
SecYEG
Online Access:https://elifesciences.org/articles/60669

Internet

https://elifesciences.org/articles/60669

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