ATP Is Required and Advances Cytokine-Induced Gap Junction Formation in Microglia In Vitro

Microglia are the immune cells in the central nervous system. After injury microglia release bioactive molecules, including cytokines and ATP, which modify the functional state of hemichannels (HCs) and gap junction channels (GJCs), affecting the intercellular communication via extracellular and int...

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Bibliographic Details
Main Authors: Pablo J. Sáez, Kenji F. Shoji, Mauricio A. Retamal, Paloma A. Harcha, Gigliola Ramírez, Jean X. Jiang, Rommy von Bernhardi, Juan C. Sáez
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/216402