Entorhinal theta-frequency input to the dentate gyrus trisynaptically evokes hippocampal CA1 LTP

Entorhinal theta-frequency input to the dentate gyrus trisynaptically evokes hippocampal CA1 LTP

There exists substantial evidence that some forms of explicit learning in mammals require long-term potentiation (LTP) at hippocampal CA3-CA1 synapses. While CA1 LTP has been well characterized at the monosynaptic level, it still remains unclear how the afferent systems to the hippocampus can initia...

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Bibliographic Details
Main Authors: Jens eStepan, Julien eDine, Thomas eFenzl, Stephanie ePolta, Gregor evon Wolff, Carsten eWotjak, Matthias eEder
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Neural Circuits
Subjects:
Caffeine
Corticosterone
Entorhinal Cortex
Hippocampus
LTP
CA1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00064/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00064/full

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