Insulin and LiCl synergistically rescue myogenic differentiation of FoxO1 over-expressed myoblasts.

Most recent studies reported that FoxO1 transcription factor was a negative regulator of myogenesis under serum withdrawal condition, a situation not actually found in vivo. Therefore, the role of FoxO1 in myogenesis should be re-examined under more physiologically relevant conditions. Here we found...

Full description

Bibliographic Details
Main Authors: Yi Ju Wu, Yen Hsin Fang, Hsiang Cheng Chi, Li Chiung Chang, Shih Ying Chung, Wei Chieh Huang, Xiao Wen Wang, Kuan Wei Lee, Shen Liang Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923792?pdf=render