HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.
Genome-wide siRNA screens have identified host cell factors important for efficient HIV infection, among which are nuclear pore proteins such as RanBP2/Nup358 and the karyopherin Transportin-3/TNPO3. Analysis of the roles of these proteins in the HIV replication cycle suggested that correct traffick...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-03-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3053352?pdf=render |