Association of the hypoxia-inducible factor-1α (HIF-1α) gene polymorphisms with prognosis in ovarian clear cell carcinoma

Association of the hypoxia-inducible factor-1α (HIF-1α) gene polymorphisms with prognosis in ovarian clear cell carcinoma

Abstract Background Ovarian clear cell carcinoma (OCCC) is the second most common ovarian cancer after serous carcinoma in Japan. OCCC has a more unfavorable clinical outcome due to a poor response to platinum-based chemotherapy, compared with serous carcinoma. Hypoxia inducible factor-1α (HIF-1α) i...

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Bibliographic Details
Main Authors: Hiroyuki Suzuki, Mitsutake Yano, Mariko Miyazawa, Masaki Miyazawa, Naoki Ogane, Kosei Hasegawa, Hitoshi Tsuda, Masayuki Yoshida, Ryugo Okagaki, Osamu Ishihara, Masanori Yasuda
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Ovarian Research
Subjects:
Ovarian clear cell carcinoma
Single-nucleotide polymorphisms (SNPs)
Hypoxia-inducible factor-1α (HIF-1α)
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13048-019-0481-9

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http://link.springer.com/article/10.1186/s13048-019-0481-9

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