Nonsterile immunity to cryptosporidiosis in infants is associated with mucosal IgA against the sporozoite and protection from malnutrition.

We conducted a longitudinal study of cryptosporidiosis from birth to three years of age in an urban slum of Dhaka Bangladesh. Fecal DNA was extracted from monthly surveillance samples and diarrheal stool samples collected from 392 infants from birth to three years. A pan-Cryptosporidium qPCR assay w...

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Bibliographic Details
Main Authors: Mamun Kabir, Masud Alam, Uma Nayak, Tuhinur Arju, Biplob Hossain, Rubaiya Tarannum, Amena Khatun, Jennifer A White, Jennie Z Ma, Rashidul Haque, William A Petri, Carol A Gilchrist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009445