Biomechanical effects on microRNA expression in skeletal muscle differentiation

We examined whether mechanical stretch affected expression of muscle-specific microRNAs (miRNAs) that regulate proliferation (miR-133a) or differentiation (miR-1, -206). Real-time quantitative RT-PCR was used to assess miRNA regulation in the murine myoblast cell line C2C12 exposed to stretch regime...

Full description

Bibliographic Details
Main Authors: Caroline Rhim, William E. Kraus, George A. Truskey
Format: Article
Language:English
Published: AIMS Press 2020-07-01
Series:AIMS Bioengineering
Subjects:
Online Access:https://www.aimspress.com/article/10.3934/bioeng.2020014/fulltext.html