Evaluation of agonist and antagonist radioligands for somatostatin receptor imaging of breast cancer using positron emission tomography

Evaluation of agonist and antagonist radioligands for somatostatin receptor imaging of breast cancer using positron emission tomography

Abstract Background The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagonists can access more binding sites on the cell surface, resulting in hig...

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Bibliographic Details
Main Authors: Iulia Dude, Zhengxing Zhang, Julie Rousseau, Navjit Hundal-Jabal, Nadine Colpo, Helen Merkens, Kuo-Shyan Lin, François Bénard
Format: Article
Language:English
Published: SpringerOpen 2017-04-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Somatostatin receptor
Breast cancer
Antagonists
Positron emission tomography
Peptides
JR11
Online Access:http://link.springer.com/article/10.1186/s41181-017-0023-y

Internet

http://link.springer.com/article/10.1186/s41181-017-0023-y

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