Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms

Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms

Abstract Clinical and epidemiological evidence suggest that loneliness is associated with severe mental disorders (SMDs) and increases the risk of cardiovascular disease (CVD). However, the mechanisms underlying the relationship between loneliness, SMDs, and CVD risk factors remain unknown. Here we...

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Bibliographic Details
Main Authors: Linn Rødevand, Shahram Bahrami, Oleksandr Frei, Aihua Lin, Osman Gani, Alexey Shadrin, Olav B. Smeland, Kevin S. O’ Connell, Torbjørn Elvsåshagen, Adriano Winterton, Daniel S. Quintana, Guy F. L. Hindley, Maren C. F. Werner, Srdjan Djurovic, Anders M. Dale, Trine V. Lagerberg, Nils Eiel Steen, Ole A. Andreassen
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-020-01142-4

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https://doi.org/10.1038/s41398-020-01142-4

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