Terbium-Based AGuIX-Design Nanoparticle to Mediate X-ray-Induced Photodynamic Therapy

Terbium-Based AGuIX-Design Nanoparticle to Mediate X-ray-Induced Photodynamic Therapy

X-ray-induced photodynamic therapy is based on the energy transfer from a nanoscintillator to a photosensitizer molecule, whose activation leads to singlet oxygen and radical species generation, triggering cancer cells to cell death. Herein, we synthesized ultra-small nanoparticle chelated with Terb...

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Bibliographic Details
Main Authors: Joël Daouk, Mathilde Iltis, Batoul Dhaini, Denise Béchet, Philippe Arnoux, Paul Rocchi, Alain Delconte, Benoît Habermeyer, François Lux, Céline Frochot, Olivier Tillement, Muriel Barberi-Heyob, Hervé Schohn
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceuticals
Subjects:
glioblastoma multiforme
AGuIX<sup>®</sup>, terbium
gadolinium
photodynamic therapy
X-ray-induced photodynamic therapy
singlet oxygen
Online Access:https://www.mdpi.com/1424-8247/14/5/396

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https://www.mdpi.com/1424-8247/14/5/396

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