Deciding the operation type according to mismatch repair status among hereditary nonpolyposis colorectal cancer patients: should a tailored approach be applied, or does one size fit all?

Deciding the operation type according to mismatch repair status among hereditary nonpolyposis colorectal cancer patients: should a tailored approach be applied, or does one size fit all?

Abstract Background Although extended colectomy (EC) was recommended for HNPCC patients, previous studies did not show significantly improved overall survival. Immunohistochemical (IHC) stain of mismatch repair (MMR) gene protein expression is now a feasible and reliable test clinically. Therefore,...

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Bibliographic Details
Main Authors: Chun-Kai Liao, Yueh-Chen Lin, Yu-Jen Hsu, Yih-Jong Chern, Jeng-Fu You, Jy-Ming Chiang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
HNPCC
MMR status
Extended colectomy
Metachronous CRC
Overall survival
Online Access:https://doi.org/10.1186/s13053-021-00186-x

Internet

https://doi.org/10.1186/s13053-021-00186-x

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