Case-control study of vitamin D, dickkopf homolog 1 (DKK1) gene methylation, VDR gene polymorphism and the risk of colon adenoma in African Americans.

Case-control study of vitamin D, dickkopf homolog 1 (DKK1) gene methylation, VDR gene polymorphism and the risk of colon adenoma in African Americans.

There are sparse data on genetic, epigenetic and vitamin D exposure in African Americans (AA) with colon polyp. Consequently, we evaluated serum 25(OH) D levels, vitamin D receptor (VDR) polymorphisms and the methylation status of the tumor suppressor gene dickkopf homolog 1 (DKK1) as risk factors f...

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Bibliographic Details
Main Authors: Hassan Ashktorab, Bijou Nguza, Mehrnaz Fatemi, Mehdi Nouraie, Duane T Smoot, Alejandro A Schäffer, Sonia S Kupfer, Carlos A Camargo, Hassan Brim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3192764?pdf=render

Internet

http://europepmc.org/articles/PMC3192764?pdf=render

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