Exploring the Involvement of NLRP3 and IL-1β in Osteoarthritis of the Hand: Results from a Pilot Study

Exploring the Involvement of NLRP3 and IL-1β in Osteoarthritis of the Hand: Results from a Pilot Study

Hand osteoarthritis (HOA) includes different subsets; a particular and uncommon form is erosive HOA (EHOA). Interleukin- (IL-) 1β plays a crucial role in the pathogenesis of osteoarthritis (OA); it is synthesized as an inactive precursor which requires the intervention of a cytosolic multiprotein co...

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Bibliographic Details
Main Authors: Antonella Fioravanti, Sara Tenti, Megan McAllister, Melody Chemaly, Amanda Eakin, Joseph McLaughlin, Anthony J. Bjourson, Elena Frati, Victoria McGilligan, Sara Cheleschi, David S. Gibson
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/2363460

Internet

http://dx.doi.org/10.1155/2019/2363460

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