No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study.

<h4>Background</h4>Studies have shown strong positive associations between serum urate (SU) levels and chronic kidney disease (CKD) risk; however, whether the relation is causal remains uncertain. We evaluate whether genetic data are consistent with a causal impact of SU level on the ris...

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Bibliographic Details
Main Authors: Daniel M Jordan, Hyon K Choi, Marie Verbanck, Ruth Topless, Hong-Hee Won, Girish Nadkarni, Tony R Merriman, Ron Do
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002725