TGF-β1-regulated miR-3691-3p targets E2F3 and PRDM1 to inhibit prostate cancer progression

TGF-β1-regulated miR-3691-3p targets E2F3 and PRDM1 to inhibit prostate cancer progression

Transforming growth factor-β1 (TGF-β1) acts as a tumor promoter in advanced prostate cancer (PCa). We speculated that microRNAs (miRNAs) that are inhibited by TGF-β1 might exert anti-tumor effects. To assess this, we identified several miRNAs downregulated by TGF-β1 in PCa cell lines and selected mi...

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Bibliographic Details
Main Authors: Yue-Mei Hu, Xiao-Li Lou, Bao-Zhu Liu, Li Sun, Shan Wan, Lei Wu, Xin Zhao, Qing Zhou, Mao-Min Sun, Kun Tao, Yong-Sheng Zhang, Shou-Li Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Asian Journal of Andrology
Subjects:
e2f transcription factor 3; mir-3691-3p; pr domain containing 1
with znf domain; prostate cancer; transforming growth factor-β1
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2021;volume=23;issue=2;spage=188;epage=196;aulast=

Internet

http://www.ajandrology.com/article.asp?issn=1008-682X;year=2021;volume=23;issue=2;spage=188;epage=196;aulast=

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