STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration

STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration

Recent studies have shown that STAT3 negatively regulates the proliferation of muscle satellite cells (MuSCs) and injury-induced muscle regeneration. These studies have been largely based on STAT3 inhibitors, which may produce off-target effects and are not cell type-specific in vivo. Here, we exami...

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Bibliographic Details
Main Authors: Han Zhu, Fang Xiao, Gang Wang, Xiuqing Wei, Lei Jiang, Yan Chen, Lin Zhu, Haixia Wang, Yarui Diao, Huating Wang, Nancy Y. Ip, Tom H. Cheung, Zhenguo Wu
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Subjects:
STAT3
Pax7
muscle satellite cells
muscle regeneration
self-renewal
dystrophin
fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716309597

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http://www.sciencedirect.com/science/article/pii/S2211124716309597

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