A novel in vitro toxicological approach to identify chemicals with a prostate-mediated effect on male reproduction

Prostate, an overlooked target in in vitro alternative methods, is critical for male fertility. Within the EU project ReProTect, the LNCaP cell line was used as a model system to screen chemicals affecting prostate by a tiered approach integrating two toxicological endpoints: cell viability and PSA...

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Bibliographic Details
Main Authors: S. Lorenzetti, L. Narciso, D. Marcoccia, I. Altieri
Format: Article
Language:English
Published: PAGEPress Publications 2011-01-01
Series:Journal of Biological Research
Subjects:
Online Access:http://www.pagepressjournals.org/index.php/jbr/article/view/4487