Impact of clostridial glucosylating toxins on the proteome of colonic cells determined by isotope-coded protein labeling and LC-MALDI
<p>Abstract</p> <p>Background</p> <p>The anaerobe <it>Clostridium difficile </it>produces two major virulence factors toxin A and B that inactivate Rho proteins by glucosylation of a pivotal threonine residue. Purified toxins induce reorganization of the cyt...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-08-01
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Series: | Proteome Science |
Subjects: | |
Online Access: | http://www.proteomesci.com/content/9/1/48 |