Impact of clostridial glucosylating toxins on the proteome of colonic cells determined by isotope-coded protein labeling and LC-MALDI

Impact of clostridial glucosylating toxins on the proteome of colonic cells determined by isotope-coded protein labeling and LC-MALDI

<p>Abstract</p> <p>Background</p> <p>The anaerobe <it>Clostridium difficile </it>produces two major virulence factors toxin A and B that inactivate Rho proteins by glucosylation of a pivotal threonine residue. Purified toxins induce reorganization of the cyt...

Full description

Bibliographic Details
Main Authors: Just Ingo, Gerhard Ralf, Jochim Nelli, Pich Andreas
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Proteome Science
Subjects:
<it>C. difficile</it>-associated diarrhea
colonic cells
ICPL™
relative quantification
Toxin A
Online Access:http://www.proteomesci.com/content/9/1/48

Internet

http://www.proteomesci.com/content/9/1/48

Similar Items