ES-cell derived hematopoietic cells induce transplantation tolerance.

BACKGROUND: Bone marrow cells induce stable mixed chimerism under appropriate conditioning of the host, mediating the induction of transplantation tolerance. However, their strong immunogenicity precludes routine use in clinical transplantation due to the need for harsh preconditioning and the requi...

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Bibliographic Details
Main Authors: Sabrina Bonde, Kun-Ming Chan, Nicholas Zavazava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2527660?pdf=render