Relevance of HLA-DQB1*02 Allele in the Genetic Predisposition of Children with Celiac Disease: Additional Cues from a Meta-Analysis

Relevance of HLA-DQB1*02 Allele in the Genetic Predisposition of Children with Celiac Disease: Additional Cues from a Meta-Analysis

<i>Background and Objectives:</i> Celiac disease (CD) is a multifactorial immune-mediated disorder, triggered by the ingestion of gluten in genetically-predisposed subjects carrying MHC-DQ2 and -DQ8 heterodimers, which are encoded by four HLA-DQ allelic variants, overall. This meta-analy...

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Bibliographic Details
Main Authors: Cristina Capittini, Annalisa De Silvestri, Chiara Rebuffi, Carmine Tinelli, Dimitri Poddighe
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Medicina
Subjects:
celiac disease
children
HLA-DQB1*02
screening
first-degree relatives
Online Access:https://www.mdpi.com/1010-660X/55/5/190

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https://www.mdpi.com/1010-660X/55/5/190

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