Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.

Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.

BACKGROUND: The zinc finger protein Znf202 is a transcriptional suppressor of lipid related genes and has been linked to hypoalphalipoproteinemia. A functional role of Znf202 in lipid metabolism in vivo still remains to be established. METHODOLOGY AND PRINCIPAL FINDINGS: We generated mouse Znf202 ex...

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Bibliographic Details
Main Authors: Carlos L J Vrins, Ruud Out, Peter van Santbrink, André van der Zee, Tokameh Mahmoudi, Martine Groenendijk, Louis M Havekes, Theo J C van Berkel, Ko Willems van Dijk, Erik A L Biessen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585336?pdf=render

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http://europepmc.org/articles/PMC3585336?pdf=render

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