Distinct anti-proliferative effects of herbal melanin on human acute monocytic leukemia THP-1 cells and embryonic kidney HEK293 cells

Distinct anti-proliferative effects of herbal melanin on human acute monocytic leukemia THP-1 cells and embryonic kidney HEK293 cells

Abstract Background Herbal melanin (HM) is a dark pigment extracted from the seed coat of Nigella sativa L. and known to exert biological effects via toll-like receptor 4 (TLR4). Recently, TLR4 was described as involved in natural programmed cell death (apoptosis). Tumor and embryonic cells are used...

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Bibliographic Details
Main Authors: Adila El-Obeid, Hala Alajmi, Mashael Harbi, Wesam Bin Yahya, Hamad Al-Eidi, Monira Alaujan, Adil Haseeb, Thadeo Trivilegio, Alshaimaa Alhallaj, Saleh Alghamdi, Abdul-Wali Ajlouni, Sabine Matou-Nasri
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Herbal melanin
THP-1
Human embryonic kidney
HEK293
Toll-like receptor 4
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12906-020-02944-1

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http://link.springer.com/article/10.1186/s12906-020-02944-1

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