Distinct anti-proliferative effects of herbal melanin on human acute monocytic leukemia THP-1 cells and embryonic kidney HEK293 cells
Abstract Background Herbal melanin (HM) is a dark pigment extracted from the seed coat of Nigella sativa L. and known to exert biological effects via toll-like receptor 4 (TLR4). Recently, TLR4 was described as involved in natural programmed cell death (apoptosis). Tumor and embryonic cells are used...
Main Authors: | Adila El-Obeid, Hala Alajmi, Mashael Harbi, Wesam Bin Yahya, Hamad Al-Eidi, Monira Alaujan, Adil Haseeb, Thadeo Trivilegio, Alshaimaa Alhallaj, Saleh Alghamdi, Abdul-Wali Ajlouni, Sabine Matou-Nasri |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | BMC Complementary Medicine and Therapies |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12906-020-02944-1 |
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