Construction and preservation of a stable and highly expressed recombinant Helicobacter pylori vacuolating cytotoxin A with apoptotic activity

Construction and preservation of a stable and highly expressed recombinant Helicobacter pylori vacuolating cytotoxin A with apoptotic activity

Abstract Background H. pylori is closely related to the occurrence and development of various digestive gastritis, peptic ulcer and mucosa-associated lymphoid tissue (MALT) lymphoma. H. pylori is also a class I carcinogen of gastric cancer. VacA is the only exocrine toxin of H. pylori, which plays a...

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Bibliographic Details
Main Authors: Ling-Zhi Yuan, Xiao Shi, Dan Tang, Shao-Peng Zheng, Zhi-Ming Xiao, Fen Wang
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Microbiology
Subjects:
Helicobacter pylori
VacA recombinant protein
Expression
Purification
Preservation
Apoptosis
Online Access:https://doi.org/10.1186/s12866-021-02262-7

Internet

https://doi.org/10.1186/s12866-021-02262-7

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