The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection.

The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection.

<h4>Background</h4>Faster fibrosis progression and hepatic steatosis are hallmarks of HIV/HCV coinfection. A single nucleotide polymorphism (SNP) of the PNPLA3-gene is associated with development of non-alcoholic steatohepatitis and a worse outcome in alcoholic liver disease. However, th...

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Main Authors: Bernhard Scheiner, Mattias Mandorfer, Philipp Schwabl, Berit Anna Payer, Theresa Bucsics, Simona Bota, Maximilian C Aichelburg, Katharina Grabmeier-Pfistershammer, Albert Stättermayer, Peter Ferenci, Michael Trauner, Markus Peck-Radosavljevic, Thomas Reiberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0143429

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https://doi.org/10.1371/journal.pone.0143429

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