Inhibition of histo-blood group antigen binding as a novel strategy to block norovirus infections.

Noroviruses (NoVs) are the most important viral pathogens that cause epidemic acute gastroenteritis. NoVs recognize human histo-blood group antigens (HBGAs) as receptors or attachment factors. The elucidation of crystal structures of the HBGA-binding interfaces of a number of human NoVs representing...

Full description

Bibliographic Details
Main Authors: Xu-Fu Zhang, Ming Tan, Monica Chhabra, Ying-Chun Dai, Jarek Meller, Xi Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3716607?pdf=render