Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse.

The gelatinases, matrix metalloproteinases (MMP)-2 and MMP-9, are thought to be key mediators of secondary damage in adult animal models of brain injury. Moreover, an acute increase in these proteases in plasma and brain extracellular fluid of adult patients with moderate-to-severe traumatic brain i...

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Bibliographic Details
Main Authors:	Bridgette D Semple, Linda J Noble-Haeusslein, Major Gooyit, Kayleen G Tercovich, Zhihong Peng, Trung T Nguyen, Valerie A Schroeder, Mark A Suckow, Mayland Chang, Jacob Raber, Alpa Trivedi
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4654502?pdf=render

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http://europepmc.org/articles/PMC4654502?pdf=render

Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse.

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