Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte DysfunctionSummary

Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte DysfunctionSummary

Background & Aims: Retention of bile acids in the blood is a hallmark of liver failure. Recent studies have shown that increased serum bile acid levels correlate with bacterial infection and increased mortality. However, the mechanisms by which circulating bile acids influence patient outcom...

Full description

Bibliographic Details
Main Authors: Julia Leonhardt, Raphael S. Haider, Christoph Sponholz, Silke Leonhardt, Julia Drube, Katrin Spengler, Diana Mihaylov, Sophie Neugebauer, Michael Kiehntopf, Nevin A. Lambert, Andreas Kortgen, Tony Bruns, Frank Tacke, Carsten Hoffmann, Michael Bauer, Regine Heller
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Liver Failure
Bile Acids
TGR5
GPBAR1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21000175

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X21000175

Similar Items