Dengue reporter virus particles for measuring neutralizing antibodies against each of the four dengue serotypes.

The lack of reliable, high-throughput tools for characterizing anti-dengue virus (DENV) antibodies in large numbers of serum samples has been an obstacle in understanding the impact of neutralizing antibodies on disease progression and vaccine efficacy. A reporter system using pseudoinfectious DENV...

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Bibliographic Details
Main Authors: Kimberly Mattia, Bridget A Puffer, Katherine L Williams, Ritela Gonzalez, Meredith Murray, Emily Sluzas, Dan Pagano, Sandya Ajith, Megan Bower, Eli Berdougo, Eva Harris, Benjamin J Doranz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3212561?pdf=render