Evaluating the ability of the pairwise joint site frequency spectrum to co-estimate selection and demography

The ability to infer the parameters of positive selection from genomic data has many important implications, from identifying drug-resistance mutations in viruses to increasing crop yield by genetically integrating favorable alleles. Although it has been well-described that selection and demography...

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Bibliographic Details
Main Authors: Lisha eMathew, Jeffrey D. Jensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00268/full