Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network.

Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. In the pancreas, the atonal-related bHLH gene Neurogenin3 (Neurog3) controls endocrine cell fate specification in uncommitted progenitor cells. Therefore...

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Bibliographic Details
Main Authors: Francis C Lynn, Lidia Sanchez, Ramon Gomis, Michael S German, Rosa Gasa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2413403?pdf=render