Identification of Rare PB2-D701N Mutation from a Patient with Severe Influenza: Contribution of the PB2-D701N Mutation to the Pathogenicity of Human Influenza
Several amino acid changes have been previously implicated in adaptation of avian influenza viruses to human hosts, among them the D701N change in the PB2 polymerase subunit that also is the main determinant of avian virus pathogenesis in animal models. However, previous studies using recombinant vi...
Main Authors: | Amelia Nieto, Francisco Pozo, Matxalen Vidal-García, Manuel Omeñaca, Inmaculada Casas, Ana Falcón |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-04-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fmicb.2017.00575/full |
Similar Items
-
Corrigendum: Identification of Rare PB2-D701N Mutation from a Patient with Severe Influenza: Contribution of the PB2-D701N Mutation to the Pathogenicity of Human Influenza
by: Amelia Nieto, et al.
Published: (2017-06-01) -
D701N mutation in the PB2 protein contributes to the pathogenicity of H5N1 avian influenza viruses but not transmissibility in guinea pigs
by: Peirong eJiao, et al.
Published: (2014-11-01) -
Structural studies on MRG701 chromodomain reveal a novel dimerization interface of MRG proteins in green plants
by: Yanchao Liu, et al.
Published: (2016-09-01) -
ISA 701 and Materiality Disclosure as Methods to Minimize the Audit Expectation Gap
by: Tomasz Iwanowicz, et al.
Published: (2019-10-01) -
Expression and Functional Analysis of the Plant-Specific Histone Deacetylase HDT701 in Rice
by: Jinhui eZhao, et al.
Published: (2015-01-01)