Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma

Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma

Abstract Background Gradual loss of terminal differentiation markers and gain of stem cell-like properties is a major hall mark of cancer malignant progression. The stem cell pluripotent transcriptional factor SOX family play critical roles in governing tumor plasticity and lineage specification. Th...

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Bibliographic Details
Main Authors: Mei-Mei Li, Yun-Qiang Tang, Yuan-Feng Gong, Wei Cheng, Hao-Long Li, Fan-En Kong, Wen-Jie Zhu, Shan-Shan Liu, Li Huang, Xin-Yuan Guan, Ning-Fang Ma, Ming Liu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Oncogenic dedifferentiation
Prognostic value
Stem cell-like properties
Online Access:http://link.springer.com/article/10.1186/s12885-019-6041-2

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http://link.springer.com/article/10.1186/s12885-019-6041-2

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