Role of Acid Sphingomyelinase in the Regulation of Social Behavior and Memory.

Major depressive disorder is often associated with deficits in social and cognitive functioning. Mice transgenic for acid sphingomyelinase (t-ASM) were previously shown to have a depressive-like phenotype, which could be normalized by antidepressant treatment. Here, we investigated whether t-ASM mic...

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Bibliographic Details
Main Authors: Iulia Zoicas, Martin Reichel, Erich Gulbins, Johannes Kornhuber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5012580?pdf=render