Dexamethasone inhibits repair of human airway epithelial cells mediated by glucocorticoid-induced leucine zipper (GILZ).

Dexamethasone inhibits repair of human airway epithelial cells mediated by glucocorticoid-induced leucine zipper (GILZ).

BACKGROUND: Glucocorticoids (GCs) are a first-line treatment for asthma for their anti-inflammatory effects, but they also hinder the repair of airway epithelial injury. The anti-inflammatory protein GC-induced leucine zipper (GILZ) is reported to inhibit the activation of the mitogen-activated prot...

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Bibliographic Details
Main Authors: Jingyue Liu, Mingxiang Zhang, Chao Niu, Zhengxiu Luo, Jihong Dai, Lijia Wang, Enmei Liu, Zhou Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3615997?pdf=render

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http://europepmc.org/articles/PMC3615997?pdf=render

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